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KMID : 0357919810150010023
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Korean Journal of Pathology
1981 Volume.15 No. 1 p.23 ~ p.28
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A Study on HDL-chotesterol Levels in Neinnal and Disease Condtions
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Abstract
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More than 25 years ago, Barr et al noted the negative relationship between high
density lipoprotein (HDL) and the incidence of coronary artery disease. A number of
studies supported for it.
Recently it was known that HDL-cholesterol is more useful indicator of coronary heart
disease than total cholesterol and triglyceride. Author studied the difference of
HDL-cholesterol levels and HDL-cholesterol/total cholesterol ratio between normal male
and female subjects, and HDL-cholesterol level in patients of coronary heart disease,
diabetes mellitus, liver disease and gastrointestinal malignancies.
The results are as follows:
1) Mean HDL-cholesterol level of normal subjects was 44.7± 12.4 mg/d1 and those of
female and male were 48.7±14.2 mg/dl and 41.9±10.1 mg/dl respectively.
2) HDL-cholesterol/total cholesterol ratio in female was higher than that of male.
3) HDL-cholesterol level in normal subjects showed no significant changes with age.
4) The difference between HDL-cholesterol levels in patients of coronary heart disease
and diabetes mellitus and that of normal subjects was insignificant.
5) HDL-cholesterol levels in patients of liver disease and gastrointestinal malignancies
were lower than normal subjects.
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